Dickkopf1 induces enteric neurogenesis and gliogenesis in vitro if apoptosis is evaded
Abstract Neurogenesis in the postnatal enteric nervous system (ENS) is controversially discussed.Yet, deciphering the regenerative potential of the ENS is essential for our understanding and therapy of human enteric neuropathies.Dickkopf1 (DKK1) is a Wnt-antagonist and involved in the homeostasis of various tissues.We hypothesize that DKK1 could fu